diff --git a/src/wp-includes/class-wp-comment-query.php b/src/wp-includes/class-wp-comment-query.php
index 71cd525833..df1bbaf2ef 100644
--- a/src/wp-includes/class-wp-comment-query.php
+++ b/src/wp-includes/class-wp-comment-query.php
@@ -273,6 +273,8 @@ class WP_Comment_Query {
 			'orderby' => '',
 			'order' => 'DESC',
 			'parent' => '',
+			'parent__in' => '',
+			'parent__not_in' => '',
 			'post_author__in' => '',
 			'post_author__not_in' => '',
 			'post_ID' => '',
diff --git a/tests/phpunit/tests/comment/query.php b/tests/phpunit/tests/comment/query.php
index c717c83cb8..bda344cd95 100644
--- a/tests/phpunit/tests/comment/query.php
+++ b/tests/phpunit/tests/comment/query.php
@@ -1864,6 +1864,44 @@ class Tests_Comment_Query extends WP_UnitTestCase {
 		$this->assertSame( $num_queries, $wpdb->num_queries );
 	}
 
+	/**
+	 * @ticket 35677
+	 */
+	public function test_cache_should_be_sensitive_to_parent__in() {
+		global $wpdb;
+
+		$q1 = new WP_Comment_Query( array(
+			'parent__in' => array( 1, 2, 3 ),
+		) );
+
+		$num_queries = $wpdb->num_queries;
+
+		$q2 = new WP_Comment_Query( array(
+			'parent__in' => array( 4, 5, 6 ),
+		) );
+
+		$this->assertNotEquals( $num_queries, $wpdb->num_queries );
+	}
+
+	/**
+	 * @ticket 35677
+	 */
+	public function test_cache_should_be_sensitive_to_parent__not_in() {
+		global $wpdb;
+
+		$q1 = new WP_Comment_Query( array(
+			'parent__not_in' => array( 1, 2, 3 ),
+		) );
+
+		$num_queries = $wpdb->num_queries;
+
+		$q2 = new WP_Comment_Query( array(
+			'parent__not_in' => array( 4, 5, 6 ),
+		) );
+
+		$this->assertNotEquals( $num_queries, $wpdb->num_queries );
+	}
+
 	/**
 	 * @ticket 32762
 	 */