diff --git a/src/wp-admin/includes/misc.php b/src/wp-admin/includes/misc.php
index 51fa058393..e0d4ddc5bc 100644
--- a/src/wp-admin/includes/misc.php
+++ b/src/wp-admin/includes/misc.php
@@ -688,23 +688,46 @@ function set_screen_options() {
 				}
 				break;
 			default:
+				if ( '_page' === substr( $option, -5 ) || 'layout_columns' === $option ) {
+					/**
+					 * Filters a screen option value before it is set.
+					 *
+					 * The filter can also be used to modify non-standard [items]_per_page
+					 * settings. See the parent function for a full list of standard options.
+					 *
+					 * Returning false to the filter will skip saving the current option.
+					 *
+					 * @since 2.8.0
+					 * @since 5.4.2 Only applied to options ending with '_page',
+					 *              or the 'layout_columns' option.
+					 *
+					 * @see set_screen_options()
+					 *
+					 * @param bool   $keep   Whether to save or skip saving the screen option value.
+					 *                       Default false.
+					 * @param string $option The option name.
+					 * @param int    $value  The number of rows to use.
+					 */
+					$value = apply_filters( 'set-screen-option', false, $option, $value ); // phpcs:ignore WordPress.NamingConventions.ValidHookName.UseUnderscores
+				}
+
 				/**
 				 * Filters a screen option value before it is set.
 				 *
-				 * The filter can also be used to modify non-standard [items]_per_page
-				 * settings. See the parent function for a full list of standard options.
+				 * The dynamic portion of the hook, `$option`, refers to the option name.
 				 *
 				 * Returning false to the filter will skip saving the current option.
 				 *
-				 * @since 2.8.0
+				 * @since 5.4.2
 				 *
 				 * @see set_screen_options()
 				 *
-				 * @param bool     $keep   Whether to save or skip saving the screen option value. Default false.
-				 * @param string   $option The option name.
-				 * @param int      $value  The number of rows to use.
+				 * @param bool   $keep   Whether to save or skip saving the screen option value.
+				 *                       Default false.
+				 * @param string $option The option name.
+				 * @param int    $value  The number of rows to use.
 				 */
-				$value = apply_filters( 'set-screen-option', false, $option, $value ); // phpcs:ignore WordPress.NamingConventions.ValidHookName.UseUnderscores
+				$value = apply_filters( "set_screen_option_{$option}", false, $option, $value );
 
 				if ( false === $value ) {
 					return;