VIPS from Python 3 VIPS Library Using VIPS How to use the VIPS library from Python VIPS comes with a convenient, high-level Python API based on gobject-introspection. As long as you can get GOI for your platform, you should be able to use vips. The Vips.py file needs to be copied to the overrides directory of your GOI install, and you need to have the vips typelib on your GI_TYPELIB_PATH. #!/usr/bin/python import sys from gi.repository import Vips im = Vips.Image.new_from_file(sys.argv[1]) im = im.crop(100, 100, im.width - 200, im.height - 200) im = im.affine([0.9, 0, 0, 0.9]) mask = Vips.Image.new_from_array([[-1, -1, -1], [-1, 16, -1], [-1, -1, -1]], scale = 8) im = im.conv(mask) im.write_to_file(sys.argv[2]) Reading the example, the first line loads the input file. There are several other loaders: you can also load a formatted image (for example, a JPEG format image) Stuff.