diff --git a/arch/arm/src/imxrt/chip/imxrt105x_pinmux.h b/arch/arm/src/imxrt/chip/imxrt105x_pinmux.h
index b4216d958b..f1331d1583 100644
--- a/arch/arm/src/imxrt/chip/imxrt105x_pinmux.h
+++ b/arch/arm/src/imxrt/chip/imxrt105x_pinmux.h
@@ -623,10 +623,14 @@
 #define GPIO_LPI2C2_SDA_2              (GPIO_PERIPH | GPIO_ALT3 | GPIO_PADMUX(IMXRT_PADMUX_GPIO_SD_B1_10_INDEX))
 
 #define GPIO_LPI2C3_SCL_1              (GPIO_PERIPH | GPIO_ALT1 | GPIO_PADMUX(IMXRT_PADMUX_GPIO_AD_B1_07_INDEX))
-#define GPIO_LPI2C3_SCL_2              (GPIO_PERIPH | GPIO_ALT2 | GPIO_PADMUX(IMXRT_PADMUX_GPIO_EMC_22_INDEX))
+#define GPIO_LPI2C3_SCL_2              (GPIO_PERIPH | GPIO_ALT2 | GPIO_PADMUX(IMXRT_PADMUX_GPIO_EMC_22_INDEX) | \
+                                        GPIO_SION_ENABLE | IOMUX_OPENDRAIN | \
+                                        IOMUX_SPEED_MEDIUM | IOMUX_DRIVE_33OHM)
 #define GPIO_LPI2C3_SCL_3              (GPIO_PERIPH | GPIO_ALT2 | GPIO_PADMUX(IMXRT_PADMUX_GPIO_SD_B0_00_INDEX))
 #define GPIO_LPI2C3_SDA_1              (GPIO_PERIPH | GPIO_ALT1 | GPIO_PADMUX(IMXRT_PADMUX_GPIO_AD_B1_06_INDEX))
-#define GPIO_LPI2C3_SDA_2              (GPIO_PERIPH | GPIO_ALT2 | GPIO_PADMUX(IMXRT_PADMUX_GPIO_EMC_21_INDEX))
+#define GPIO_LPI2C3_SDA_2              (GPIO_PERIPH | GPIO_ALT2 | GPIO_PADMUX(IMXRT_PADMUX_GPIO_EMC_21_INDEX) | \
+                                        GPIO_SION_ENABLE | IOMUX_OPENDRAIN | \
+                                        IOMUX_SPEED_MEDIUM | IOMUX_DRIVE_33OHM)
 #define GPIO_LPI2C3_SDA_3              (GPIO_PERIPH | GPIO_ALT2 | GPIO_PADMUX(IMXRT_PADMUX_GPIO_SD_B0_01_INDEX))
 
 #define GPIO_LPI2C4_SCL_1              (GPIO_PERIPH | GPIO_ALT0 | GPIO_PADMUX(IMXRT_PADMUX_GPIO_AD_B0_12_INDEX))
diff --git a/arch/arm/src/imxrt/imxrt_lpi2c.c b/arch/arm/src/imxrt/imxrt_lpi2c.c
index 56d0c40539..ebf6bbf4b3 100644
--- a/arch/arm/src/imxrt/imxrt_lpi2c.c
+++ b/arch/arm/src/imxrt/imxrt_lpi2c.c
@@ -1285,16 +1285,18 @@ static int imxrt_lpi2c_isr_process(struct imxrt_lpi2c_priv_s *priv)
               imxrt_lpi2c_traceevent(priv, I2CEVENT_NOSTART, priv->msgc);
             }
 
+          priv->msgv++;
+          priv->msgc--;
+
           if ((priv->flags & I2C_M_READ) != 0)
             {
 #ifndef CONFIG_I2C_POLLED
               /* Stop TX interrupt */
 
               imxrt_lpi2c_modifyreg(priv, IMXRT_LPI2C_MIER_OFFSET,
-                                    LPI2C_MIER_TDIE, 0);
+                                    LPI2C_MIER_TDIE, LPI2C_MIER_RDIE);
 #endif
               /* Set LPI2C in read mode */
-
               imxrt_lpi2c_putreg(priv, IMXRT_LPI2C_MTDR_OFFSET, LPI2C_MTDR_CMD_RXD | LPI2C_MTDR_DATA((priv->dcnt - 1)));
             }
           else
@@ -1305,10 +1307,13 @@ static int imxrt_lpi2c_isr_process(struct imxrt_lpi2c_priv_s *priv)
               imxrt_lpi2c_putreg(priv, IMXRT_LPI2C_MTDR_OFFSET,
                                  LPI2C_MTDR_CMD_TXD | LPI2C_MTDR_DATA(*priv->ptr++));
               priv->dcnt--;
+              if ((priv->msgc <= 0) && (priv->dcnt == 0))
+                {
+                  imxrt_lpi2c_sendstop(priv);
+                }
           }
 
-          priv->msgv++;
-          priv->msgc--;
+
         }
       else if (priv->msgv && ((status & LPI2C_MSR_SDF) != 0))
         {
diff --git a/configs/imxrt1050-evk/include/board.h b/configs/imxrt1050-evk/include/board.h
index 9fd6abd6d7..490bc8b946 100644
--- a/configs/imxrt1050-evk/include/board.h
+++ b/configs/imxrt1050-evk/include/board.h
@@ -162,6 +162,9 @@
 #define GPIO_LPI2C1_SDA   GPIO_LPI2C1_SDA_2  /* GPIO_AD_B1_01 */
 #define GPIO_LPI2C1_SCL   GPIO_LPI2C1_SCL_2  /* GPIO_AD_B1_00 */
 
+#define GPIO_LPI2C3_SDA   GPIO_LPI2C3_SDA_2  /* GPIO_AD_B1_01 */
+#define GPIO_LPI2C3_SCL   GPIO_LPI2C3_SCL_2  /* GPIO_AD_B1_00 */
+
 /************************************************************************************
  * Public Types
  ************************************************************************************/
diff --git a/configs/imxrt1050-evk/src/imxrt_bringup.c b/configs/imxrt1050-evk/src/imxrt_bringup.c
index c4486a976b..1217a93a89 100644
--- a/configs/imxrt1050-evk/src/imxrt_bringup.c
+++ b/configs/imxrt1050-evk/src/imxrt_bringup.c
@@ -57,7 +57,7 @@
  * Private Functions
  ****************************************************************************/
 
-#if defined(CONFIG_I2C_DRIVER) && defined(CONFIG_IMXRT_LPI2C1)
+#if defined(CONFIG_I2C_DRIVER)
 static void imxrt_i2c_register(int bus)
 {
   FAR struct i2c_master_s *i2c;
@@ -114,6 +114,16 @@ int imxrt_bringup(void)
 #if defined(CONFIG_I2C_DRIVER) && defined(CONFIG_IMXRT_LPI2C1)
   imxrt_i2c_register(1);
 #endif
+#if defined(CONFIG_I2C_DRIVER) && defined(CONFIG_IMXRT_LPI2C2)
+  imxrt_i2c_register(2);
+#endif
+#if defined(CONFIG_I2C_DRIVER) && defined(CONFIG_IMXRT_LPI2C3)
+  imxrt_i2c_register(3);
+#endif
+#if defined(CONFIG_I2C_DRIVER) && defined(CONFIG_IMXRT_LPI2C4)
+  imxrt_i2c_register(4);
+#endif
+
 
   UNUSED(ret);
   return OK;