diff --git a/include/nuttx/mm/kasan.h b/include/nuttx/mm/kasan.h
index 4b1654c53e..9406bf238c 100644
--- a/include/nuttx/mm/kasan.h
+++ b/include/nuttx/mm/kasan.h
@@ -39,6 +39,7 @@
 #  define kasan_poison(addr, size)
 #  define kasan_unpoison(addr, size) addr
 #  define kasan_register(addr, size)
+#  define kasan_unregister(addr)
 #  define kasan_init_early()
 #  define kasan_reset_tag(addr) addr
 #else
@@ -126,6 +127,22 @@ FAR void *kasan_unpoison(FAR const void *addr, size_t size);
 
 void kasan_register(FAR void *addr, FAR size_t *size);
 
+/****************************************************************************
+ * Name: kasan_unregister
+ *
+ * Description:
+ *   Stop monitoring the memory range
+ *
+ * Input Parameters:
+ *   addr - range start address
+ *
+ * Returned Value:
+ *   None.
+ *
+ ****************************************************************************/
+
+void kasan_unregister(FAR void *addr);
+
 /****************************************************************************
  * Name: kasan_init_early
  *
diff --git a/mm/kasan/generic.c b/mm/kasan/generic.c
index 513279fae1..cd326ca827 100644
--- a/mm/kasan/generic.c
+++ b/mm/kasan/generic.c
@@ -274,6 +274,35 @@ void kasan_register(FAR void *addr, FAR size_t *size)
   *size -= KASAN_REGION_SIZE(*size);
 }
 
+void kasan_unregister(FAR void *addr)
+{
+  FAR struct kasan_region_s *prev = NULL;
+  FAR struct kasan_region_s *region;
+  irqstate_t flags;
+
+  flags = spin_lock_irqsave(&g_lock);
+  for (region = g_region; region != NULL; region = region->next)
+    {
+      if (region->begin == (uintptr_t)addr)
+        {
+          if (region == g_region)
+            {
+              g_region = region->next;
+            }
+          else
+            {
+              prev->next = region->next;
+            }
+
+          break;
+        }
+
+      prev = region;
+    }
+
+  spin_unlock_irqrestore(&g_lock, flags);
+}
+
 void kasan_init_early(void)
 {
   g_region_init = 0;
diff --git a/mm/mm_heap/mm_initialize.c b/mm/mm_heap/mm_initialize.c
index ef2329dc0d..6852b439ad 100644
--- a/mm/mm_heap/mm_initialize.c
+++ b/mm/mm_heap/mm_initialize.c
@@ -357,10 +357,17 @@ mm_initialize_pool(FAR const char *name,
 
 void mm_uninitialize(FAR struct mm_heap_s *heap)
 {
+  int i;
+
 #ifdef CONFIG_MM_HEAP_MEMPOOL
   mempool_multiple_deinit(heap->mm_mpool);
 #endif
 
+  for (i = 0; i < CONFIG_MM_REGIONS; i++)
+    {
+      kasan_unregister(heap->mm_heapstart[i]);
+    }
+
 #if defined(CONFIG_FS_PROCFS) && !defined(CONFIG_FS_PROCFS_EXCLUDE_MEMINFO)
 #  if defined(CONFIG_BUILD_FLAT) || defined(__KERNEL__)
   procfs_unregister_meminfo(&heap->mm_procfs);
diff --git a/mm/tlsf/mm_tlsf.c b/mm/tlsf/mm_tlsf.c
index d6241a4c5d..4c60f419bf 100644
--- a/mm/tlsf/mm_tlsf.c
+++ b/mm/tlsf/mm_tlsf.c
@@ -1416,10 +1416,17 @@ FAR void *mm_realloc(FAR struct mm_heap_s *heap, FAR void *oldmem,
 
 void mm_uninitialize(FAR struct mm_heap_s *heap)
 {
+  int i;
+
 #ifdef CONFIG_MM_HEAP_MEMPOOL
   mempool_multiple_deinit(heap->mm_mpool);
 #endif
 
+  for (i = 0; i < CONFIG_MM_REGIONS; i++)
+    {
+      kasan_unregister(heap->mm_heapstart[i]);
+    }
+
 #if defined(CONFIG_FS_PROCFS) && !defined(CONFIG_FS_PROCFS_EXCLUDE_MEMINFO)
 #  if defined(CONFIG_BUILD_FLAT) || defined(__KERNEL__)
   procfs_unregister_meminfo(&heap->mm_procfs);