diff --git a/boards/arm/cxd56xx/spresense/Kconfig b/boards/arm/cxd56xx/spresense/Kconfig
index 46cded7dac..974f77cc16 100644
--- a/boards/arm/cxd56xx/spresense/Kconfig
+++ b/boards/arm/cxd56xx/spresense/Kconfig
@@ -756,6 +756,13 @@ config CXD56_LTE_SPI5_DMAC
 
 endif # CXD56_LTE_SPI5
 
+config CXD56_LTE_LATE_INITIALIZE
+	bool "Alt1250 driver late initialize"
+	default n
+	---help---
+		LTE driver can be initialized on an application code after system booted up
+		by enabling this configuration switch.
+
 endif # CXD56_LTE
 
 config CXD56_BINARY
diff --git a/boards/arm/cxd56xx/spresense/src/cxd56_bringup.c b/boards/arm/cxd56xx/spresense/src/cxd56_bringup.c
index fa01f4860c..3b6012eb94 100644
--- a/boards/arm/cxd56xx/spresense/src/cxd56_bringup.c
+++ b/boards/arm/cxd56xx/spresense/src/cxd56_bringup.c
@@ -463,6 +463,14 @@ int cxd56_bringup(void)
     }
 #endif
 
+#if defined(CONFIG_MODEM_ALT1250) && !defined(CONFIG_CXD56_LTE_LATE_INITIALIZE)
+  ret = board_alt1250_initialize("/dev/alt1250");
+  if (ret < 0)
+    {
+      _err("ERROR: Failed to initialize ALT1250.\n");
+    }
+#endif
+
 #ifdef CONFIG_CXD56_GNSS
   ret = cxd56_gnssinitialize("/dev/gps");
   if (ret < 0)