diff --git a/arch/arm/src/stm32/Kconfig b/arch/arm/src/stm32/Kconfig
index 557f8434f0..eba911dfc5 100644
--- a/arch/arm/src/stm32/Kconfig
+++ b/arch/arm/src/stm32/Kconfig
@@ -6201,12 +6201,11 @@ config STM32_I2C_DUTY16_9
 config STM32_I2C_DMA
 	bool "I2C DMA Support"
 	default n
-	depends on STM32_I2C && STM32_STM32F40XX && STM32_DMA1
+	depends on STM32_I2C && STM32_STM32F40XX && STM32_DMA1 && !I2C_POLLED
 	---help---
 		This option enables the DMA for I2C transfers.
 		Note: The user can define CONFIG_I2C_DMAPRIO: a custom priority value for the
 		I2C dma streams, else the default priority level is set to medium.
-		Note: This option is compatible with CONFIG_I2C_POLLED.
 
 endmenu