diff -uNr ruby-2.4.2/addr2line.c ruby-2.4.2.mod/addr2line.c
--- ruby-2.4.2/addr2line.c	2016-10-18 18:09:08.000000000 +0300
+++ ruby-2.4.2.mod/addr2line.c	2017-09-15 12:00:56.242805138 +0300
@@ -451,7 +451,7 @@
     /* Ideally we should check 4 paths to follow gnu_debuglink,
        but we handle only one case for now as this format is used
        by some linux distributions. See GDB's info for detail. */
-    static const char global_debug_dir[] = "/usr/lib/debug";
+    static const char global_debug_dir[] = "@TERMUX_PREFIX@/lib/debug";
     const size_t global_debug_dir_len = sizeof(global_debug_dir) - 1;
     char *p;
 
diff -uNr ruby-2.4.2/dln_find.c ruby-2.4.2.mod/dln_find.c
--- ruby-2.4.2/dln_find.c	2016-06-02 19:52:15.000000000 +0300
+++ ruby-2.4.2.mod/dln_find.c	2017-09-15 12:00:28.522805158 +0300
@@ -72,6 +72,10 @@
 
     if (!path) {
 	path =
+        "@TERMUX_PREFIX@/bin" PATH_SEP
+        "@TERMUX_PREFIX@/bin/applets" PATH_SEP
+        "/system/xbin" PATH_SEP
+        "/system/bin" PATH_SEP
 	    "/usr/local/bin" PATH_SEP
 	    "/usr/ucb" PATH_SEP
 	    "/usr/bin" PATH_SEP
diff -uNr ruby-2.4.2/lib/drb/gw.rb ruby-2.4.2.mod/lib/drb/gw.rb
--- ruby-2.4.2/lib/drb/gw.rb	2015-12-16 07:07:31.000000000 +0200
+++ ruby-2.4.2.mod/lib/drb/gw.rb	2017-09-15 12:06:04.592804917 +0300
@@ -99,8 +99,8 @@
 
 front = DRb::GW.new
 
-s1 = DRb::DRbServer.new('drbunix:/tmp/gw_b_a', front)
-s2 = DRb::DRbServer.new('drbunix:/tmp/gw_b_c', front)
+s1 = DRb::DRbServer.new('drbunix:@TERMUX_PREFIX@/tmp/gw_b_a', front)
+s2 = DRb::DRbServer.new('drbunix:@TERMUX_PREFIX@/tmp/gw_b_c', front)
 
 s1.thread.join
 s2.thread.join
@@ -131,9 +131,9 @@
 require 'foo'
 
 obj = Foo.new('a')
-DRb.start_service("drbunix:/tmp/gw_a", obj)
+DRb.start_service("drbunix:@TERMUX_PREFIX@/tmp/gw_a", obj)
 
-robj = DRbObject.new_with_uri('drbunix:/tmp/gw_b_a')
+robj = DRbObject.new_with_uri('drbunix:@TERMUX_PREFIX@/tmp/gw_b_a')
 robj[:a] = obj
 
 DRb.thread.join
@@ -146,9 +146,9 @@
 
 foo = Foo.new('c', nil)
 
-DRb.start_service("drbunix:/tmp/gw_c", nil)
+DRb.start_service("drbunix:@TERMUX_PREFIX@/tmp/gw_c", nil)
 
-robj = DRbObject.new_with_uri("drbunix:/tmp/gw_b_c")
+robj = DRbObject.new_with_uri("drbunix:@TERMUX_PREFIX@/tmp/gw_b_c")
 
 puts "c->b"
 a = robj[:a]
diff -uNr ruby-2.4.2/lib/mkmf.rb ruby-2.4.2.mod/lib/mkmf.rb
--- ruby-2.4.2/lib/mkmf.rb	2017-09-15 11:42:55.362805911 +0300
+++ ruby-2.4.2.mod/lib/mkmf.rb	2017-09-15 13:57:38.032800130 +0300
@@ -1551,7 +1551,7 @@
     if path ||= ENV['PATH']
       path = path.split(File::PATH_SEPARATOR)
     else
-      path = %w[/usr/local/bin /usr/ucb /usr/bin /bin]
+      path = %w[@TERMUX_PREFIX@/bin @TERMUX_PREFIX@/bin/applets /system/xbin /system/bin /usr/local/bin /usr/ucb /usr/bin /bin]
     end
     file = nil
     path.each do |dir|
diff -uNr ruby-2.4.2/lib/resolv.rb ruby-2.4.2.mod/lib/resolv.rb
--- ruby-2.4.2/lib/resolv.rb	2016-11-24 01:57:30.000000000 +0200
+++ ruby-2.4.2.mod/lib/resolv.rb	2017-09-15 13:49:49.152800465 +0300
@@ -172,7 +172,7 @@
       require 'win32/resolv'
       DefaultFileName = Win32::Resolv.get_hosts_path
     rescue LoadError
-      DefaultFileName = '/etc/hosts'
+      DefaultFileName = '@TERMUX_PREFIX@/etc/hosts'
     end
 
     ##
@@ -957,7 +957,7 @@
         return { :nameserver => nameserver, :search => search, :ndots => ndots }
       end
 
-      def Config.default_config_hash(filename="/etc/resolv.conf")
+      def Config.default_config_hash(filename="@TERMUX_PREFIX@/etc/resolv.conf")
         if File.exist? filename
           config_hash = Config.parse_resolv_conf(filename)
         else
diff -uNr ruby-2.4.2/lib/rubygems/config_file.rb ruby-2.4.2.mod/lib/rubygems/config_file.rb
--- ruby-2.4.2/lib/rubygems/config_file.rb	2016-09-28 03:57:53.000000000 +0300
+++ ruby-2.4.2.mod/lib/rubygems/config_file.rb	2017-09-15 13:47:05.912800582 +0300
@@ -81,7 +81,7 @@
 
         path.strip
       rescue LoadError
-        RbConfig::CONFIG["sysconfdir"] || "/etc"
+        RbConfig::CONFIG["sysconfdir"] || "@TERMUX_PREFIX@/etc"
       end
     end
 
diff -uNr ruby-2.4.2/lib/rubygems/defaults.rb ruby-2.4.2.mod/lib/rubygems/defaults.rb
--- ruby-2.4.2/lib/rubygems/defaults.rb	2017-09-15 11:42:55.262805911 +0300
+++ ruby-2.4.2.mod/lib/rubygems/defaults.rb	2017-09-15 13:59:05.152800068 +0300
@@ -116,7 +116,7 @@
 
   def self.default_bindir
     if defined? RUBY_FRAMEWORK_VERSION then # mac framework support
-      '/usr/bin'
+      '@TERMUX_PREFIX@/bin'
     else # generic install
       RbConfig::CONFIG['bindir']
     end
diff -uNr ruby-2.4.2/lib/webrick/config.rb ruby-2.4.2.mod/lib/webrick/config.rb
--- ruby-2.4.2/lib/webrick/config.rb	2016-12-07 14:59:48.000000000 +0200
+++ ruby-2.4.2.mod/lib/webrick/config.rb	2017-09-15 12:03:02.402805048 +0300
@@ -35,7 +35,7 @@
       :Logger         => nil,   # default: WEBrick::Log.new
       :ServerSoftware => "WEBrick/#{WEBrick::VERSION} " +
                          "(Ruby/#{RUBY_VERSION}/#{RUBY_RELEASE_DATE})",
-      :TempDir        => ENV['TMPDIR']||ENV['TMP']||ENV['TEMP']||'/tmp',
+      :TempDir        => ENV['TMPDIR']||ENV['TMP']||ENV['TEMP']||'@TERMUX_PREFIX@/tmp',
       :DoNotListen    => false,
       :StartCallback  => nil,
       :StopCallback   => nil,