diff -uNr PyPanel-2.4/setup.py PyPanel-2.4.mod/setup.py
--- PyPanel-2.4/setup.py	2005-06-23 04:48:49.000000000 +0300
+++ PyPanel-2.4.mod/setup.py	2017-12-12 17:52:16.997058670 +0200
@@ -3,10 +3,10 @@
 from distutils import sysconfig
 
 # Full paths to imlib2-config and freetype-config, adjust as needed -
-configs = ["/usr/bin/freetype-config", "/usr/bin/imlib2-config"]
+configs = ["@TERMUX_PREFIX@/bin/freetype-config", "@TERMUX_PREFIX@/bin/imlib2-config"]
 
 # Adjust or add any additional include directories here -
-idirs   = ["/usr/X11R6/include"]
+idirs   = ["@TERMUX_PREFIX@/include"]
 
 # Add any additional library directories here -
 ldirs   = []
@@ -15,7 +15,7 @@
 cargs   = ["-Wall"]
 
 # Full path to libImlib2 shared library
-imlib2  = "/usr/lib/libImlib2.so.1"
+imlib2  = "@TERMUX_PREFIX@/lib/libImlib2.so.1"
 
 #------------------------------------------------------------------------------
 # The rest of this script should not need to be modified! 
@@ -85,7 +85,7 @@
 if len(sys.argv) > 1 and sys.argv[1] != "sdist":
     for line in fileinput.input(["pypanel"], inplace=1):
         if fileinput.isfirstline():
-            print "#!%s -OO" % sys.executable
+            print "#!%s" % sys.executable
         else:
             print line,